The Trauma Pill

January 31st, 2006 | researchmaterial

A “trauma pill” could blot out memories of harrowing events for combat veterans and survivors of accidents or terrorism, say Canadian researchers.

Most memories decay naturally, but people under extreme stress pump an abnormal amount of stress hormones during the event — so the memories are stored differently, said Dr. Alain Brunet, professor of psychiatry at McGill University in Montreal.

“If you have (Post Traumatic Stress Disorder) your memory is so fresh it’s as if the event is happening now,” he said. “For a person to have that vivid flashback certain hormones are released by the brain. If you can block these, the memory is weakened or even removed completely.”

Brunet and colleagues had 20 people suffering from PTSD recall their experiences as vividly as possible in therapy sessions, after being given doses of propranolol — a beta-blocker used to treat high blood pressure, angina and abnormal heart rhythms. Preliminary findings indicate the PTSD sufferers experienced fewer flashbacks and less severe symptoms after taking the drug.

(”Trauma Pill” — pre-fab band name)

15 Responses to “The Trauma Pill”

  1. Sweet. Eternal Sunshine in a pill.

  2. That which does not kill us can now be convienently forgotten.

  3. Presumably this will also be available in some sort of ‘morning after’ version as well. For quickly erasing the sordid results of those accursed beer goggles.

  4. That could be the only reason to thank my PTSD then. Too bad I don’t need those pills, I already have a goldfish memory.

  5. This sounds just like the drug Col. Fury describes in Marvel’s Secret War: Book Five. It’s kind of scary knowing that memories could be wiped out so easily. Heh, if only the “trauma pill” had been invented in the DC universe, certain superheroes could have mind-wiped those villains properly! Take THAT Zatanna!

  6. Propanolol also is also used to treat anxiety…especially its somatic effects (i.e. sweaty palms, queasy stomach, etc.) A side effect is depression comes with long term use. It also induces asthma attacks.

  7. Is this sort of reverse roofies? Someone gets raped, pilled, and wakes up in the morning with a sore ass and no idea why?

    Just wait, you’ll see this in a year being sold in topical format as a lube.

  8. Love me till you drug me baby. Sounds like the newscum have found their soma.

  9. Propranolol is actually a very old drug, and has been generic for a long time. It slows the heart rate by blocking beta-adrenergic receptors which are activated during “fight or flight” responses and is often used in heart patients to control heart rate. It doesn’t really have many side effects other than some people feel a little sleepy, but nothing major, nothing like roofies or whatever, but it does prevent your heart from racing, excess sweating, rapid breathing etc.

    It has been a great tool for a lot of other problems as well, such as performance anxiety, anxiety from air travel, etc. So if you’re a concert pianist and you need your nerves to be rock solid but you can’t take a valium which will make you sleepy and dull, you take a propranolol and your hands don’t shake without any mental side effects. It doesn’t alter your consciousness, so you might still be terrified of the audience and of failure, but since your autonomic nervous system’s fight or flight response is muted, your hands are steady and you don’t piss yourself. This story is really interesting because it suggests if you don’t feel the physical effects of such terrifying experiences, you don’t record them traumatically. It’s not a mind control drug or anything so dramatic, it’s just blocks the physical effects of nervousness and that’s apparently enough to block traumatic memory. Freaking genius really.

  10. Read “On the Sea of Memory: a Journey from Forgetting to Remembering” by Jonathan Cott (an author and Rolling Stone journalist who did the last interview of John Lennon before the killing.) This is a new book that includes all kinds of wild-sounding tales about memory, including this one about beta-blockers and PTS.
    Cott, a wonderful writer, received electroshock treatments for serious depression and subsequently forgot 15 years of his life, 1985 to 2000. In this book he explores memory from all kinds of angles — medical to African storytelling and Tibetan Buddhist remembrance of past lives. In between he writes his own story.
    No, this business with beta-blockers and PTS isn’t a joke and isn’t Brave New World. Traumatic memories, as I understand, never diminish in intensity and so can ruin the lives of people who’ve already been through too much.

  11. So, per Quitter’s information - soldiers could take this drug before a firefight and really kick ass.

  12. Those familiar with the past forty years or medical research originating from McGill University will tell you that it is usually thorough, but at times can be poorly designed, inconsistent, and laced with dramatic pronouncements. As such, it is wise to take such announcements with a dose of scepticism, sleep on it, and then call me in the morning.

  13. The conclusions reached are a little bit much, I agree. It sounds like the researchers are making some extraordinary claims from what is really a simple finding. This isn’t some miracle drug or high tech memory blocker. It’s just a drug that prevents you from feeling the physical side-effects of nervousness and fear. You are still afraid, and you still can be nervous or fearful, you just don’t sweat and your heart doesn’t beat out of your chest. Everyone knows that feeling of terror, your stomach dropping down to your toes, and that impending feeling of doom that makes you shake, sweat and faint. This drug wouldn’t prevent you from feeling afraid, but it would prevent you from experiencing the physical feelings of being afriad.

    Per Bill’s comment, yes, it probably could help soldiers stay calm before a fight, but I think their training and experience is more than adequate and probably safer. If you took beta blockers before a fight you’d be cool as a fish, but in the end they prevent full performance of your body. It might be a bad idea to prevent higher heart rates and autonomic responses in the heat of a battle. But for those who are unused to responding to life-or-death situations or are completely undone by their fear it is a useful drug and based one these researchers’ claims might prevent the long-term storage of traumatic memories.

  14. […] Warrenellis.com — The Trauma Pill Read “On the Sea of Memory: a Journey from Forgetting to Remembering” by Jonathan Cott (an author and Rolling Stone journalist who did the last interview of John Lennon before the killing.) This is a new book that includes all kinds of wild-sounding tales about memory, including this one about beta-blockers and PTS. Cott, a wonderful writer, received electroshock treatments for serious depression and subsequently forgot 15 years of his life, 1985 to 2000. In this book he explores memory from all kinds of angles — medical to African storytelling and Tibetan Buddhist remembrance of past lives. In between he writes his own story. No, this business with beta-blockers and PTS isn’t a joke and isn’t Brave New World. Traumatic memories, as I understand, never diminish in intensity and so can ruin the lives of people who’ve already been through too much. […]

  15. I suffered from really bad PTSD. Tried the usual gamut of psychiatric drugs and they messed me up badly. Did research on mind-body interaction, and realised that flash-backs caused my pulse to rise - caused fight-or-flight reactions in an ever-increasing spiral both mental and physical. 3 years ago, researched ways of stopping the cycle. Betablockers stop my pulse from rising, which short-circuits the mind-body onterplay (and in this country they cost about 5% of what psychiatric drugs cost). Took very low doses for about 6 months. Seemed to break the cycle and I am a different person today. In stressful situations, will take a dose to avoid anxiety and have not yet had a serious flashback. Brilliant stuff!!

Miss Piggy?s Teaches of Peaches

Coilhouse - 20 Nov 09

Every time an issue of the magazine goes to print, things somehow turn Highly Inappropriate here at Coilhouse. This is apparent to anyone who was there on Twitter during the hours of our final revision deadline last night. And it’s only going to get worse before Issue 04’s out. So to celebrate, a video of Miss Piggy singing “Fuck the Pain Away” by Peaches. It’s that kind of day.

[via Shannon]


Post tags: Madness, Music, Puppetry

claytoncubitt: Will Blanche, ?The Newly Constructed Towers of...

Brian Wood - 20 Nov 09



claytoncubitt:

Will Blanche, ?The Newly Constructed Towers of the World Trade Center Seen From the South Side on West Street, May, 1973? (via These Americans)

See also: Mitch Epstein, ?West Side Highway, New York City? [looking towards World Trade Center] 1977

Percy Jackson trailer

Kung Fu Monkey - 20 Nov 09

Seriously, if I were 12, this would have melted my brain. I love this trailer.

JOURNAL: How to Break and Open Source Insurgency

John Robb - 20 Nov 09

Short Answer:  divide it.

It's long been my contention that Iraq was stabilized at an acceptable level of controlled chaos due to a happy accident by al Qaeda (in an attempt to expand/lead the loose insurgency in a new direction).  What did they do?   They blew up the Golden Mosque in Samara in 2006.  This act of symbolic terrorism did indeed disrupt social networks as anticipated, however the consequences were ultimately disastrous for the Iraqi open source insurgency.  

Baghdad_Ethnic_2007_late_smThe reason for this is it broke the dynamics of the open source insurgency in ways the US and Iraqi government's COIN efforts could not.  First, it created a permanent split between Sunni and Shiite insurgent groups/militias.  Coopetition ended.  Second, it motivated large Shiite militias to start an ethnic cleansing of Sunni areas.  This put acute pressure on Sunni guerrilla groups who were too small (by design to avoid US counter-pressure) to defend themselves against large militias operating in the open.  The result was an opening, very close to the one I described in my 2005 NYTimes OpEd, that allowed the US to convert Sunni guerrilla groups into militias that were not loyal to the central government (in direct contradiction to its COIN manual).   

It's a nice example of the dynamics of many to many conflict, social network disruption, and the development open source counterinsurgency.

See this excellent description at the blog, "Musings on Iraq" for more detail on the ethnic cleansing operations.  It also includes this money quote: "the majority of the Sunni insurgency gave up and switched sides to align with the Americans rather than face annihilation at the hands of the Shiite militias, Al Qaeda in Iraq, or the United States."

NOTE:  it's pretty clear from the above that social network disruption (either through attacks on symbolic targets or blood and guts terrorism) is like playing horseshoes with live hand grenades.  It's ultimately a losing strategy for advancing an open source insurgency.  Social network disruption is very likely to break standing order 6:  don't fork the insurgency.

Twitter Updates for 2009-11-20

Girl Farts - 20 Nov 09

LINKS: 20 NOV 09

John Robb - 20 Nov 09

Some random items of interest:

  • Vigilante militias in Rio are displacing the drug gangs -- favelas under the control of militias has grown from 108 in 2005 to 400 in 2008 (out of 965).  Why?  They have a better (albeit parasitic) conflict/business model than the drug gangs since they act as a substitute for missing public goods/services normally supplied by the government.  First, they provide a minimal level of security and conflict adjudication.  Second, they make more money than the drug gangs by "taxing" everything from propane to cable TV to the gray market.  
  • US gray economy estimated at $1 Trillion (not including criminal, outside of the evasion of taxes and regulation, activities) and growing faster than the "legal" economy.  
  • Proposal and wiki for an open source fabrication lab.
  • Somali pirates are expanding operations into the Indian ocean.  The combination of positive feedback loops (maritime insurance + rapid payoffs by crisis negotiators) and legal ambiguity (the biggest fear of a western navy and governments is that they might arrest a pirate -- prompting a massive/expensive legal tussle with few certain penalties and the forced extension of a visa to the former pirate once he is released from his short incarceration).  Is a franchise model for other locales possible?
  • Yes-we-can-secede
  • A business group in Ciudad Juarez asks for UN peacekeepers.  Hilarious. "Ciudad Juarez, population 1.5 million, has an average of seven homicides a day, with the total at 1,986 for this year through mid-October."
  • Seccession.net.  County based secession effort.  

Untitled Post

blissblog - 20 Nov 09

Yume no Byouin Project

Jean Snow - 20 Nov 09

Yume no Byouin Project

Beautiful (and simple) site design featuring the illustrative work of Yorifuji Bunpei. Via Paul Baron.

Kodai

Jean Snow - 20 Nov 09

Kodai

Coming up at the Kakitsubata gallery in Nakameguro is the show “Kodai,” running from November 25 until December 6.

Kodai

Kap Bambino

jwz - 20 Nov 09